Sodium/iodide-symporter: distribution in different mammals and role in entero-thyroid circulation of iodide
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منابع مشابه
Sodium/iodide-symporter: distribution in different mammals and role in entero-thyroid circulation of iodide.
UNLABELLED The sodium (Na+)/iodide (I-)-symporter (NIS) is abundantly expressed and accumulates iodide in thyroid follicular cells. The NIS is also found in extrathyroidal tissues, particularly gastric mucosa. Controversies exist on the localization of extrathyroidal NIS. We have studied the presence of both NIS peptide and NIS messenger RNA (mRNA) in the digestive tract and thyroid from differ...
متن کاملSodium/iodide-symporter: distribution in different mammals and role in entero-thyroid circulation of iodide
The sodium (Na)/iodide (I)-symporter (NIS) is abundantly expressed and accumulates iodide in thyroid follicular cells. The NIS is also found in extrathyroidal tissues, particularly gastric mucosa. Controversies exist on the localization of extrathyroidal NIS. We have studied the presence of both NIS peptide and NIS messenger RNA (mRNA) in the digestive tract and thyroid from different mammals. ...
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15 صفحه اولSodium iodide symporter (NIS) and thyroid.
idase (TPO) and incorporation into tyrosyl residues along the thyroglobulin (Tg) backbone. The thyroid hormones T3 and T4 are synthesized by coupling of two iodotyrosine residues and stored in the colloid. All of these steps are stimulated by pituitary-derived thyroid stimulating hormone (TSH), which interacts with the TSH receptor at the basolateral membrane of thyroidal cells, through the cAM...
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ژورنال
عنوان ژورنال: Acta Physiologica Scandinavica
سال: 2002
ISSN: 0001-6772
DOI: 10.1046/j.1365-201x.2002.00968.x